王聰，男，博士，生命科學(xué)學(xué)院，首聘教授。
細(xì)胞與發(fā)育生物學(xué)系
Email：wangc@scau.edu.cn
研究興趣及方向
以擬南芥和大豆為材料，圍繞植物減數(shù)分裂同源重組、命運(yùn)決定和表觀遺傳重編的分子機(jī)制等核心問題，結(jié)合多組學(xué)、細(xì)胞學(xué)、生物化學(xué)等手段從多維度解析調(diào)控減數(shù)分裂的分子遺傳和表觀遺傳機(jī)制，加深對于遺傳變異的認(rèn)知，為農(nóng)作物育種和人類生殖健康提供理論支持。主要研究方向?yàn)椋?）植物減數(shù)分裂的命運(yùn)決定和遺傳調(diào)控；2）植物的表觀遺傳重編程；3）大豆花形態(tài)建成。以通訊或第一作者（含共同）在PNAS（3篇）、The Plant Cell（2篇）和Plant Physiology（2篇）等高水平期刊共發(fā)表論文10篇。獲得國家自然科學(xué)基金面上項(xiàng)目（2024-2027）、青年科學(xué)基金（2021-2023）和博士后創(chuàng)新人才（2019）的支持。受邀在全國植物生物學(xué)大會(huì)和發(fā)育生物學(xué)大會(huì)等會(huì)議做報(bào)告。
教育經(jīng)歷
2013.09-2019.01 復(fù)旦大學(xué), 生命科學(xué)學(xué)院，生物化學(xué)系，博士；
2009.09-2013.06 蘭州大學(xué)，生命科學(xué)學(xué)院，生物科學(xué)，學(xué)士
工作經(jīng)歷
2023.02-今 華南農(nóng)業(yè)大學(xué)，教授
2019.4-2023.01 復(fù)旦大學(xué)，生命科學(xué)學(xué)院，博士后；
主持的科研課題
2024.01-2027.12 國家自然科學(xué)基金面上項(xiàng)目
2021.01-2023.12 國家自然科學(xué)基金青年科學(xué)基金
2019.11-2021.11 第66批中國博士后科學(xué)基金面上項(xiàng)目
2019.05-2021.05 2019年度博士后創(chuàng)新人才支持計(jì)劃
代表性論文（#一作，*通訊）（名字加黑）
Wang C, Wang Y. Meiosis requires m6A modification for selection of targets in plants.New Phytologist,244(6), 2118–2120 (2024).
Wang C, Chen ZY,Copenhaver GP*, Wang YX*.Heterochromatin in plant meiosis.Nucleus, 2024, 15 (1): 2328719
WangTY,Wang HK, Lian QC, Jia Q, You CJ,Copenhaver GP*;Wang C*; Wang YX*. HEI10 is Subject to Phase Separation and Mediates RPA1a Degradation during Meiotic Interference-sensitive Crossover Formation.Proc Natl Acad Sci U S A, 2023,120,(52): e2310542120.
Wang C, Li X, Huang J, Ma H, Wang C R, Wang YX*. Isolation of Meiocytes and Cytological Analyses of Male Meiotic Chromosomes in Soybean, Lettuce, and Maize. In: Riechmann, J.L., Ferrándiz, C. (eds) Flower Development. Methods Mol. Biol (book series). 2023;2686:219-239.
Li JC#,Wang C#, Liang W, Zhang J, Jiang CK, Liu Y, Ren Z, Ci D, Chang J, Han S, Deng XW, Wang YX*, Qian WQ*. Functional importance and divergence of plant apurinic/apyrimidinic endonucleases in somatic and meiotic DNA repair. Plant Cell. 2023; 35:2316-2331
Wang C#, Huang JY#, Li YP, Zhang J, He CP, Li TY, Jiang DH, Dong AW, Ma H*, Copenhaver GP*, Wang YX*; DNA Polymerase Epsilon Binds Histone H3.1-H4 and Recruits MORC1 to Mediate Meiotic Heterochromatin Condensation,Proc Natl Acad Sci U S A, 2022, 119(43):e2213540119. IF: 12.779
Wang C; Huang JY; Zhang J; Yu Y; Copenhaver GP; You CJ*; Wang YX*; DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis,Proc Natl Acad Sci U S A, 2022, 119(41):e2208441119. IF: 12.779
Huang JY#,Wang C#, Li X, Fang XL, Huang N, Wang Y, Ma H, Wang YX*, Copenhaver GP*. Conservation and divergence in the meiocyte sRNAomes of Arabidopsis, soybean and cucumber.Plant Physiology, 2020, 82:301-317.
Huang JY#,Wang C#, Wang HF, Lu PL, Zheng BL, Ma H, Copenhaver GP*, Wang YX*. Meiocyte-specific and AtSPO11-1-dependent small RNAs and their association with meiotic gene expression and recombination.Plant Cell, 2019, 31:1-21. In brief by the editor in the same issue.
Wang C#, Huang JY#, Zhang J, Wang HK, Han YP, Copenhaver GP, Ma H, Wang YX*. The Largest Subunit of DNA Polymerase Delta is Important for Normal Formation of Meiotic Type I Crossovers in Arabidopsis.Plant Physiology, 2019, 179: 446-459.
Huang JY#, Li X#, Wang C, Wang YX. Evaluation of Crossover Number, Distribution, and Interference Using Cytological Assays in Arabidopsis. Current Protocal, 2022, 1(12).
He CP#, Chen ZY#, Zhao YY, Yu Y, Wang HK, Wang C, Copenhaver GP, Ji Qi, Wang YX. Histone demethylase IBM1-mediated meiocyte gene expression ensures meiotic chromosome synapsis and recombination. PLoS Genet, 2022, 18:e1010041.
Huang JY#, Chenjiang You Cj#, Cong Wang C, Yingxiang Wang YX, and Copenhaver GP*. Identifying Small RNAs and Analyzing Their Association with Gene Expression Using Isolated Arabidopsis Male Meiocytes, Methods Mol Biol (book series), 2022, 2484:23-41
Wang HK#, Xu WY#, Sun YJ, Lian QC, Wang C, Yu CY, He CP, Wang J, Ma H, Copenhaver GP*, Wang YX*, The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants. PLoS Genetics, 2020, 16(6): e1008849.
Huang JY#, Cheng ZH#, Wang C, Hong Y, Su H, Wang J, Copenhaver GP, Ma H*, Wang YX*, Formation of Interference-Sensitive Meiotic Cross-Overs Requires Sufficient DNA Leading-Strand Elongation, Proc Natl Acad Sci U S A, 2015, 112(40): 12534-12539.
黃霽月;王聰;王應(yīng)祥;減數(shù)分裂重組的分子遺傳機(jī)制研究進(jìn)展及在作物育種中的應(yīng)用,華南農(nóng)業(yè)大學(xué)學(xué)報(bào), 2022, 43(6): 17-35
