胡 喆
首聘副教授 性別：男
所屬單位：微生物學(xué)系
辦公室：生命科學(xué)學(xué)院北-213
Email：zhehu@scau.edu.cn
工作經(jīng)歷
2021.06至今，華南農(nóng)業(yè)大學(xué)生命科學(xué)學(xué)院副教授
2017.05-2020.11，伊利諾伊大學(xué)厄巴納-香檳分校（UIUC），微生物系，博士后
教育經(jīng)歷
2013.09-2016.12 理學(xué)博士，生物化學(xué)與分子生物學(xué)，華南農(nóng)業(yè)大學(xué)
2010.09-2013.06 理學(xué)碩士，微生物學(xué)，華南農(nóng)業(yè)大學(xué)
2006.09-2010.06 工學(xué)學(xué)士，生物工程，合肥工業(yè)大學(xué)
主講課程
《微生物學(xué)》，《微生物學(xué)實驗》。
研究領(lǐng)域
病原微生物脂肪酸及其衍生物代謝
科研項目
1 廣東省基礎(chǔ)與應(yīng)用基礎(chǔ)研究基金區(qū)域聯(lián)合基金-青年基金項目 ,野油菜黃單胞菌3-酮脂酰ACP還原酶編碼基因fabG2轉(zhuǎn)錄調(diào)控研究, 2021-10至2024-09，在研，主持。
2 華南農(nóng)業(yè)大學(xué)高層次人才科研啟動項目，2021-2026，在研，主持。
發(fā)表論文
1.Chen, Y.C., Hu Z#., Zhang W. B., Yin Y., Zhong C. Y., Mo W. Y., Yu Y.H., Ma J. C., and Wang H.H. 2022. Hetl-like phosphopantetheiny transferase posttranslationally modifies acyl carrier protein in Xanthomonas campestris. Mol Plant Microbe Interact, (accepted), Doi: org/10.1094/MPMO- 10-21-0240-R.
2.Hu Z., Ma J. C., Tong W.H., Zhu L., Wang H.H. and Cronan J.E. 2021. Escherichia coli FabG 3-ketoacyl-ACP reductase proteins lacking the assigned catalytic triad residues are active enzymes. J Biol Chem 296:100365.
3.Hu Z., and Cronan J. E. The primary step of biotin synthesis in Mycobacteria. 2020. Proc Natl Acad Sci USA 117(38): 23794-23801.
4.Srinivas S#., Hu Z#., and Cronan J. E. 2019. Escherichia coli vectors having stringently repressible replication origins allow streamlining of CRISPR/Cas9 gene editing. Plasmid103:53-62.
5.Hu Z, Dong H, Ma JC, Yu Y, Li KH, Guo QQ, Zhang C, Zhang WB, Cao X, Cronan JE, Wang H. 2018. Novel Xanthomonas campestris long-chain-specific 3-oxoacyl-acyl carrier protein reductase involved in diffusible signal factor synthesis. mBio 9:e00596-18.
6.Cao X.Y., Zhu L., Song X. J., Hu Z., and Cronan J. 2018. E. Protein moonlighting elucidates the essential human pathway catalyzing lipoic acid assembly on its cognate enzymes. Proc Natl Acad Sci USA 115(30): 7063-7072.
7.Cao X.Y., Zhu L., Hu Z., and Cronan J.E. 2017. Expression and Activity of the BioH Esterase of Biotin Synthesis is Independent of Genome Context. Sci Rep 7: 2141.
8.Yu Y, Hu Z, Dong H, Ma J, Wang H. 2016. Xanthomonas campestris FabH is required for branched-chain fatty acid and DSF-family quorum sensing signal biosynthesis. Sci Rep 6:32811.
9.Mao Y. H., Li F., Ma J. C., Hu Z. and Wang H. H. Functional replacement of 3-Oxoacyl-Acyl Carrier Protein Reductase (FabG) in fatty acid synthesis of Sinorhizobium meliloti by overexpression of NodG. Mol Plant Microbe Interact, 2016, 29(6): 458-467.
10.Feng S. X., Ma J. C., Yang J., Hu Z., Bi H. K., Sun Y. R. and Wang H. H. Ralstonia solanacearum fatty acid composition is determined by interaction of two 3-ketoacyl-acyl carrier protein reductases encoded on separate replicons. BMC microbiology,2015,15(1): 223, DOI 10.1186/s12866-015-0554-x.
11.Mao Y. H., Li F., Ma J. C., Hu Z. and Wang H. H. Ralstonia solanacearum RSp0194 Encodes A Novel 3-Keto-Acyl Carrier Protein Synthase III. Plos one, 2015, DOI: 10.1371/journal.pone.0136261.
12.馬金成，周俊超，吳楚云，胡喆，王海洪。苜蓿中華根瘤菌desA基因功能的鑒定。生物化學(xué)與生物物理進(jìn)展，2015，42(08)：740-749。
13.馬金成，羅彪，胡喆，王海洪。乳酸乳球菌fabZ1和fabZ2基因功能的鑒定.生物化學(xué)與生物物理進(jìn)展，2014，41(08)：777-786。
14.胡喆，馬金成，蔣晶晶，王海洪。苜蓿中華根瘤菌fabA和fabB基因功能的鑒定。生物化學(xué)與生物物理進(jìn)展，2013，40(11)：1148-1159。
15.Zhu L., Bi H., Ma J., Hu Z., Zhang W., Cronan J. E. and Wang H. The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistance. mBio, 2013, 4(5): e00613-13.
